• Masui · Jun 2013

    Comparative Study

    [Safety and beneficial effects of spinal morphine on the postoperative course of elderly patients undergoing surgical fixation of the femoral neck fracture].

    • Tatsunori Watanabe, Takashi Fujiwara, Takashi Mochida, Ippei Watanabe, and Hiroshi Baba.
    • Department of Anesthesiology, Niigata University Graduate School of Medical and Dental Sciences, Niigata 951-8510.
    • Masui. 2013 Jun 1; 62 (6): 665-9.

    BackgroundWe performed a retrospective study of the efficacy and safety of spinal anesthesia with 0.1 mg morphine in the postoperative course of elderly patients with femoral neck fracture.MethodsSixty patients with ages averaging 84 years participated in this study. Surgery was performed under spinal anesthesia. Patients were assigned to either a group receiving of 0.1 mg morphine added to isobaric bupivacaine (Group M) or a group receiving of isobaric bupivacaine alone (Group B). The frequency of analgesic use and the occurrence of adverse side effects during the first 48 hours after surgery were compared between the two groups.ResultsIn the first 24 hours, the patients in Group M needed significantly less analgesics compared to Group B. The incidence of adverse side effects did not differ significantly between the groups, although nausea had a tendency to increase in Group M. One patient in Group M showed a mild decrease in oxygen saturation.ConclusionsThe spinal administration of 0.1 mg morphine had beneficial effects and was safe in the postoperative period of elderly patients with femoral neck fracture provided that sufficient observation was given.

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