• Maria Sargianou, George Panos, Andreas Tsatsaris, Charalambos Gogos, and Anna Papa.
• Division of Infectious Diseases, Department of Internal Medicine, Patras University General Hospital, Patras, Greece; Department of Microbiology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, 54006, Greece.
• Int. J. Infect. Dis. 2013 Dec 1; 17 (12): e1160-5.

BackgroundThe Crimean-Congo hemorrhagic fever virus (CCHFV) presents a wide distribution, with the Balkan Peninsula being among the endemic regions. To date, only one CCHF case has been reported in Greece; however, based on seroprevalence data, there is evidence that CCHFV circulates in the country. Achaia is a prefecture in western Greece that has not previously been studied for CCHFV.ObjectivesThe aim of this study was to estimate the seroprevalence of CCHFV in humans in Achaia Prefecture, Greece, and to assess possible factors playing a role in seropositivity.MethodsA total of 207 serum samples from people of all age groups, from both urban and rural areas, were prospectively collected and tested for IgG antibodies against CCHFV.ResultsThe overall seroprevalence was 3.4%, with significant differences among municipalities. An agro-pastoral occupation, contact with sheep and goats, former tick bite, increasing age, and living at an altitude of ≥400 m, on specific land cover types, were significantly associated with CCHFV seropositivity.ConclusionsA relatively high seroprevalence was detected in a previously unstudied region of Greece, where CCHFV infection seems to occur mainly through tick bites. Further investigations are needed to identify the circulating CCHFV strains in Greece, in order to gain a better understanding of CCHFV ecology and epidemiology in the country.Copyright © 2013 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

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