• Peter Jan van Laar, Oterdoom D L Marinus DL Department of Neurosurgery, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Gert J Ter Horst, Arjen L J van Hulzen, Eva K L de Graaf, Hans Hoogduin, Linda C Meiners, and J Marc C van Dijk.
• Department of Radiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
• World Neurosurg. 2016 Sep 1; 93: 410-2.

BackgroundIn deep brain stimulation (DBS), accurate placement of the lead is critical. Target definition is highly dependent on visual recognition on magnetic resonance imaging (MRI). We prospectively investigated whether the 7-T MRI enabled better visualization of targets and led to better placement of leads compared with the 1.5-T and the 3-T MRI.MethodsThree patients with PD (mean, 55 years) were scanned on 1.5-, 3-, and 7-T MRI before surgery. Tissue contrast and signal-to-noise ratio were measured. Target coordinates were noted on MRI and during surgery. Differences were analyzed with post-hoc analysis of variance.ResultsThe 7-T MRI demonstrated a significant improvement in tissue visualization (P < 0.005) and signal-to-noise ratio (P < 0.005). However, no difference in the target coordinates was found between the 7-T and the 3-T MRI.ConclusionsAlthough the 7-T MRI enables a significant better visualization of the DBS target in patients with PD, we found no clinical benefit for the placement of the DBS leads.Copyright © 2016 Elsevier Inc. All rights reserved.

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