• Cerebrovascular diseases · Jan 2007

    Fibromuscular dysplasia may herald symptomatic recurrence of cervical artery dissection.

    • J M de Bray, G Marc, V Pautot, B Vielle, A Pasco, P Lhoste, and F Dubas.
    • Department of Neurology, University Hospital Angers, Angers, France. jmdebray@chu-angers.fr
    • Cerebrovasc. Dis. 2007 Jan 1; 23 (5-6): 448-52.

    BackgroundThe prevalence of fibromuscular dysplasia (FMD) in patients with cervical artery dissection (CAD) is unknown. Our objectives were to assess the risk of CAD recurring as a stroke or a transient ischemic attack and the association of these events with FMD.MethodsWe prospectively included and followed 103 consecutive patients who had been admitted for a CAD. The median follow-up was 4 years (range 4 months to 10 years). The main criteria for inclusion were a mural hematoma demonstrated by cervical magnetic resonance imaging and/or signs suggesting CAD on 2 other investigations. FMD was diagnosed on the so-called string of beads pattern by digital subtraction angiography.ResultsFive patients had CAD recurrence (60% occurred late). Four of these 5 patients had FMD. In 4 patients, CAD recurrence involved another cervical artery.ConclusionThe rate of symptomatic CAD recurrence was 1% per year and was often related to FMD.Copyright 2007 S. Karger AG, Basel.

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