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Ned Tijdschr Geneeskd · Jan 1998
Case Reports[Circulatory arrest following sulprostone administration in postpartum hemorrhage].
- C C Beerendonk, L F Massuger, A M Lucassen, J G Lerou, and P P van den Berg.
- Afd. Obstetrie-Gynaecologie, Academisch Ziekenhuis, Nijmegen.
- Ned Tijdschr Geneeskd. 1998 Jan 24; 142 (4): 195-7.
AbstractIn a woman aged 39 cardiac arrest occurred 3.5 hours after administration of 250 micrograms sulprostone directly into the uterine wall for a post-partum haemorrhage after manual removal of the placenta. A long period of resuscitation was necessary. After further evaluation the woman demonstrated specific contraindications to the administration of sulprostone. as formulated by the French authorities: age > 35 years, heavy cigarette smoking, and cardiovascular risk factors. In the Netherlands sulprostone is registered for intravenous administration only. We would strongly advise against administration directly into the uterine wall.
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