• Clin. Microbiol. Infect. · Jan 2011

    Case Reports

    Intercontinental spread from Israel to Colombia of a KPC-3-producing Klebsiella pneumoniae strain.

    • J A Lopez, A Correa, S Navon-Venezia, A L Correa, J A Torres, D F Briceño, M C Montealegre, J P Quinn, Y Carmeli, and M V Villegas.
    • Hospital Pablo Tobón Uribe, Medellín, Colombia.
    • Clin. Microbiol. Infect. 2011 Jan 1; 17 (1): 52-6.

    AbstractIn 2008, an increase in the prevalence of carbapenem-resistant Klebsiella pneumoniae was noted in a 286-bed tertiary case hospital in Colombia, where 84 patients (32 infected and 52 colonized) had positive cultures. The identified index patient came from Israel for a liver transplantation. High level carbapenem resistance was observed. Polymyxin B and tigecycline were the only two antibiotics that remained active. PCR-restriction fragment length polymorphism analysis and sequencing revealed blaKPC-3 in the major clone, which was indistinguishable from the K. pneumoniae carbapenemase-3-producing clone described previously in Israel. This exemplifies the threat posed by the global spread of K. pneumoniae carbapenemase-producing pathogens.© 2010 The Authors. Journal Compilation © 2010 European Society of Clinical Microbiology and Infectious Diseases.

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