• J Headache Pain · Jul 2013

    Migraine prevalence in patients with atrial septal defect.

    • Yuji Kato, Takeshi Hayashi, Toshiki Kobayashi, and Norio Tanahashi.
    • J Headache Pain. 2013 Jan 1;14:63.

    BackgroundPatients with a patent foramen ovale have a high prevalence of migraine with aura (MA). However, whether patients with an atrial septal defect (ASD) have a high prevalence of migraine remains unclear. The present study aimed to determine the prevalence of migraine and its clinical characteristics in patients with ASD.FindingsNinety-five patients (age ≥ 20 years) who had undergone percutaneous ASD closure responded to a questionnaire used by neurologists to diagnose migraine either with or without aura. We diagnosed migraine before ASD closure according to the criteria of the International Headache Society. The overall prevalence of migraine seemed to be higher in the present study than in the Japanese general population (24.2% vs. 9.4%, respectively). All patients with MA were female and significantly younger than those without migraine (p < 0.01).ConclusionsOur findings suggested that the susceptibility to the development of MA differs according to sex and age in patients with cardiac shunt.

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