• J Clin Neurosci · Aug 2014

    Case Reports

    Sickle cell disease and posterior reversible leukoencephalopathy.

    • Nimeshan Geevasinga, Catherine Cole, Geoffrey K Herkes, Yael Barnett, Jamie Lin, and Merrilee Needham.
    • Department of Neurology, Royal North Shore Hospital, Reserve Road, St Leonards, Sydney, NSW 2065, Australia; Western Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address: ngeevasi@med.usyd.edu.au.
    • J Clin Neurosci. 2014 Aug 1; 21 (8): 1329-32.

    AbstractSickle cell disease can present with neurological manifestations. One such presentation is with posterior reversible leukoencephalopathy also known as reversible posterior leukoencephalopathy. The condition is classically described as reversible over time; it commonly presents with oedematous changes involving the white matter of the occipital and parietal regions. Only a few patients with the association between sickle cell disease and posterior reversible leukoencephalopathy have been described in the adult literature. We present two patients from our institutions to emphasise the association between the two conditions and summarise the published cases in the literature.Copyright © 2014 Elsevier Ltd. All rights reserved.

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