• Pancreas · Mar 2012

    Percutaneous catheter drainage for infective pancreatic necrosis: is it always the first choice for all patients?

    • Zhihui Tong, Weiqin Li, Wenkui Yu, Yanxia Geng, Lu Ke, Yao Nie, Jiakui Sun, Haibin Ni, Xinying Wang, Xianghong Ye, Ning Li, and Jieshou Li.
    • Department of Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, China.
    • Pancreas. 2012 Mar 1; 41 (2): 302-5.

    ObjectiveTo learn the clinical outcome of percutaneous catheter drainage (PCD) for patients with infective pancreatic necrosis and the possible influencing factors.MethodsA retrospective review of medical records of patients with infective pancreatic necrosis who received PCD as the first choice for treatment in the recent 2 years. The patients were divided into 2 groups: (1) PCD success group and (2) PCD alteration group. Characteristics, complications, and PCD process were compared.ResultsIn this study, 19 of 34 patients were cured by PCD alone (55.9%), whereas open necrosectomy were needed for 15 patients (44.1%). Between these 2 groups, most baseline and clinical characteristics did not show any statistical difference, including the number and size of catheter used and the bacterial culture result. The PCD alteration group had higher mean computed tomographic density (P = 0.012) and larger distribution range of infected pancreatic necrosis (4.53 ± 1.35 vs 5.93 ± 1.62; P = 0.009) than the PCD success group (P < 0.01). The logistic regression analysis revealed the same facts.ConclusionThe mean computed tomographic density and distribution range of infective pancreatic necrosis could significantly influence the success rate of PCD; higher values of them indicate less appropriate for PCD; thus, it should be considered seriously before the treatment decision.

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