• Manjunath Hulmani, B Nandakishore, M Ramesh Bhat, D Sukumar, Jacintha Martis, Ganesh Kamath, and M K Srinath.
• Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, India.
• Indian Dermatol Online J. 2014 Jan 1; 5 (1): 25-9.

BackgroundErythroderma is a morphological reaction pattern of skin having many underlying causes and finding the etiology helps in the proper management of erythroderma cases.AimTo evaluate the clinical profile, etiology of erythroderma and to correlate clinical diagnosis with histopathology.Materials And MethodsThis study was performed at the department of dermatology, Father Muller Medical College and Hospital, Mangalore, South India. We studied 30 consecutive cases of erythroderma with respect to the epidemiological, clinical and histological data. Clinico-histological correlation was analyzed for etiology of erythroderma.ResultsThe mean age of onset was 52.3 years with a male to female ratio of 14:1. In addition to erythroderma, other co-existent features included pruritus, fever, lymphadenopathy, and edema. Of the pre-existing dermatoses, psoriasis was the most common (33.3%) disease followed by eczema (20%), atopic dermatitis (6.6%), pityriasis rubra pilaris (3.3%) and drug-induced erythroderma (16.6%). In 16.6% of cases, etiology could not be ascertained. Clinico-histopathological correlation could be established in 73.3% of cases.ConclusionClinical features were identical irrespective of etiology. Detailed clinico-histopathological examination helps to establish the etiology of erythroderma.

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