• J Am Diet Assoc · Jul 2008

    Randomized Controlled Trial Multicenter Study

    A large randomized individual and group intervention conducted by registered dietitians increased adherence to Mediterranean-type diets: the PREDIMED study.

    • Itziar Zazpe, Ana Sanchez-Tainta, Ramon Estruch, Rosa María Lamuela-Raventos, Helmut Schröder, Jordi Salas-Salvado, Dolores Corella, Miquel Fiol, Enrique Gomez-Gracia, Fernando Aros, Emilio Ros, Valentina Ruíz-Gutierrez, Pablo Iglesias, Manuel Conde-Herrera, and Miguel Angel Martinez-Gonzalez.
    • Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain.
    • J Am Diet Assoc. 2008 Jul 1; 108 (7): 1134-44; discussion 1145.

    ObjectiveTo assess the effectiveness of an intervention aimed to increase adherence to a Mediterranean diet.DesignA 12-month assessment of a randomized primary prevention trial.Subjects/SettingsOne thousand five hundred fifty-one asymptomatic persons aged 55 to 80 years, with diabetes or > or =3 cardiovascular risk factors.InterventionParticipants were randomly assigned to a control group or two Mediterranean diet groups. Those allocated to the two Mediterranean diet groups received individual motivational interviews every 3 months to negotiate nutrition goals, and group educational sessions on a quarterly basis. One Mediterranean diet group received free virgin olive oil (1 L/week), the other received free mixed nuts (30 g/day). Participants in the control group received verbal instructions and a leaflet recommending the National Cholesterol Education Program Adult Treatment Panel III dietary guidelines.Main Outcome MeasuresChanges in food and nutrient intake after 12 months.Statistical AnalysesPaired t tests (for within-group changes) and analysis of variance (for between-group changes) were conducted.ResultsParticipants allocated to both Mediterranean diets increased their intake of virgin olive oil, nuts, vegetables, legumes, and fruits (P<0.05 for all within- and between-group differences). Participants in all three groups decreased their intake of meat and pastries, cakes, and sweets (P<0.05 for all). Fiber, monounsaturated fatty acid, and polyunsaturated fatty acid intake increased in the Mediterranean diet groups (P<0.005 for all). Favorable, although nonsignificant, changes in intake of other nutrients occurred only in the Mediterranean diet groups.ConclusionsA 12-month behavioral intervention promoting the Mediterranean diet can favorably modify an individual's overall food pattern. The individual motivational interventions together with the group sessions and the free provision of high-fat and palatable key foods customary to the Mediterranean diet were effective in improving the dietary habits of participants in this trial.

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