• Cutis · Apr 2003

    Case Reports

    Pemphigus erythematosus associated with anti-DNA antibodies and multiple anti-ENA antibodies: a case report.

    • Noah S Scheinfeld, Kenneth L Howe, Damian P DiCostanzo, Errol Craig, and Steven R Cohen.
    • Department of Dermatology, Beth Israel Medical Center, Albert Einstein College of Medicine, New York, New York, USA. scheinfeld@earthlink.net
    • Cutis. 2003 Apr 1; 71 (4): 303-6.

    AbstractPemphigus erythematosus (PE) is an autoimmune blistering disease combining features of pemphigus foliaceus (PF) and systemic lupus erythematosus (SLE). We report a case of PE associated with anti-double-stranded DNA (anti-dsDNA), anti-Smith (anti-Sm), anti-Ro (anti-SSA), and antiribonucleoprotein (anti-RNP) antibodies. This case required extensive immunosuppressive therapy. We treated our patient with a combination of systemic steroids, intramuscular gold injections, azathioprine, and hydroxychloroquine. The patient's response was complete remission--evaluated clinically, serologically, and immunohistochemically.

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