• Psychiatr Pol · Nov 2012

    Review Case Reports

    [Psychotic symptoms and cognitive impairment in neurosarcoidosis. Case report and review of literature].

    • Małgorzata Gaweł, Izabela Domitrz, Dorota Dziewulska, Andrzej Dabrowski, Witold Przyjałkowski, Marek Gołebiowski, and Hubert Kwieciński.
    • Katedra i Klinika Neurologii WUM, Warszawa.
    • Psychiatr Pol. 2012 Nov 1; 46 (6): 1099-108.

    AbstractClinical involvement of the nervous system occurs in about 5% of patients with sarcoidosis. We describe a fatal case of a young patient with neurosarcoidosis with a relatively rare psychotic syndrome in the course of neurosarcoidosis, presenting itself as a depressive syndrome with delusions. The neurological manifestations consisted of cerebellar symptoms, peripheral neuropathy and general epileptic seizures. Cerebrospinal fluid examination, serum angiotensin-converting enzyme level, magnetic resonance imaging, chest radiography, gallium isotope scanning and other tests were used as diagnostic tools. He was treated with steroids, methotrexate and neuroleptics ineffectively. The patient died because of complications related to neurosarcoidosis. The diagnosis of neurosarcoidosis was confirmed by autopsy.

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