• J Headache Pain · Aug 2014

    Refractory chronic migraine: a consensus statement on clinical definition from the European Headache Federation.

    • Paolo Martelletti, Zaza Katsarava, Christian Lampl, Delphine Magis, Lars Bendtsen, Andrea Negro, Michael Bjørn Russell, Dimos-Dimitrios D Mitsikostas, and Rigmor Højland Jensen.
    • Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy. paolo.martelletti@uniroma1.it.
    • J Headache Pain. 2014 Aug 28; 15: 47.

    AbstractThe debate on the clinical definition of refractory Chronic Migraine (rCM) is still far to be concluded. The importance to create a clinical framing of these rCM patients resides in the complete disability they show, in the high risk of serious adverse events from acute and preventative drugs and in the uncontrolled application of therapeutic techniques not yet validated.The European Headache Federation Expert Group on rCM presents hereby the updated definition criteria for this harmful subset of headache disorders. This attempt wants to be the first impulse towards the correct identification of these patients, the correct application of innovative therapeutic techniques and lastly aim to be acknowledged as clinical entity in the next definitive version of the International Classification of Headache Disorders 3 (ICHD-3 beta).

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