• Psychiatry research · Apr 2012

    Regional gray matter changes in obsessive-compulsive disorder: relationship to clinical characteristics.

    • Cornelia Exner, Ulrike Zetsche, Vera Martin, Winfried Rief, and Andreas Jansen.
    • Department of Clinical Psychology and Psychotherapy, University of Marburg, Marburg, Germany. exnerc@uni-leipzig.de
    • Psychiatry Res. 2012 Apr 30; 202 (1): 74-6.

    AbstractRegional brain volumes were compared between 23 participants with obsessive-compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset.Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

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