• Lancet Infect Dis · Mar 2016

    Review

    Tropheryma whipplei infection and Whipple's disease.

    • Thomas Marth, Verena Moos, Christian Müller, Federico Biagi, and Thomas Schneider.
    • Division of Internal Medicine, Krankenhaus Maria Hilf, Daun, Germany. Electronic address: t.marth@krankenhaus-daun.de.
    • Lancet Infect Dis. 2016 Mar 1; 16 (3): e13-22.

    AbstractRecent advances in medical microbiology, epidemiology, cellular biology, and the availability of an expanded set of diagnostic methods such as histopathology, immunohistochemistry, PCR, and bacterial culture have improved our understanding of the clinical range and natural course of Tropheryma whipplei infection and Whipple's disease. Interdisciplinary and transnational research activities have contributed to the clarification of the pathogenesis of the disorder and have enabled controlled trials of different treatment strategies. We summarise the current knowledge and new findings relating to T whipplei infection and Whipple's disease.Copyright © 2016 Elsevier Ltd. All rights reserved.

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