• World Neurosurg · Sep 2016

    Spinal Schwannoma and Meningioma Mimicking a Single Mass at the Craniocervical Junction Subsequent to Remote Radiation Therapy for Acne Vulgaris.

    • Brandon D Liebelt, Ali S Haider, William J Steele, Chandan Krishna, and J Bob Blacklock.
    • Department of Neurosurgery, Houston Methodist Neurological Institute, Houston, Texas, USA. Electronic address: bdliebelt@houstonmethodist.org.
    • World Neurosurg. 2016 Sep 1; 93: 484.e13-6.

    BackgroundSchwannomas and meningiomas are relatively common tumors of the nervous system. They have been reported in the literature as existing concurrently as a single mass, but very rarely have they been shown to present at the craniocervical junction.Case DescriptionWe present a rare and interesting case of a patient previously treated with radiation therapy for acne vulgaris and who presented to us with a concurrent schwannoma and meningioma of the craniocervical junction mimicking a single mass.ConclusionsThese tumors can be solitary or mixed masses, and are known to be associated with certain disease processes such as long-term sequelae of radiation therapy and neurofibromatosis type 2. The precise mechanism behind the formation of these tumors is unknown; however, molecular cues in the tumor microenvironment may play a role.Copyright © 2016 Elsevier Inc. All rights reserved.

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