• Nishita Kothary, Laura Lock, Daniel Y Sze, and Lawrence V Hofmann.
• Department of Interventional Radiology, Stanford University Medical Center, Stanford, CA 94305, USA. kothary@stanford.edu
• Clin Lung Cancer. 2009 Sep 1; 10 (5): 360-3.

PurposeThis study was undertaken to compare the diagnostic accuracy and complication rate of computed tomography (CT)-guided percutaneous lung biopsies of lung nodules1.5 cm in diameter.Patients And MethodsA total of 139 patients (age range, 18-89 years; mean, 62.5 years) underwent CT-guided percutaneous fine-needle aspiration biopsy or 20-gauge core biopsy using an automated biopsy gun. In 37 patients, the lung nodule measured 1.5 cm (mean, 2.8 cm). Diagnostic accuracy was determined by cytopathology results. Major and minor complications were documented.ResultsOverall diagnostic accuracy, pneumothorax rate, and thoracostomy tube insertion rates were 67.6%, 34.5%, and 5%, respectively. Of the 98 patients with malignancy, 77 patients (78.6%) had a definite diagnostic biopsy. Overall, nodules>1.5 cm were statistically more likely to result in a diagnostic specimen (73.5%) than nodules1.5 cm than in thoseConclusionOverall, diagnostic accuracy of CT-guided percutaneous lung biopsy of lung nodules1.5 cm. However, the diagnostic accuracy for malignancy is high in both groups, with a low risk of complications.

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