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Asian J Transfus Sci · Jul 2011
Safety of type and screen method compared to conventional antiglobulin crossmatch procedures for compatibility testing in Indian setting.
- Rajendra Chaudhary and Nitin Agarwal.
- Department of Transfusion Medicine, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
- Asian J Transfus Sci. 2011 Jul 1; 5 (2): 157-9.
BackgroundOver the past 30 years, pretransfusion tests have undergone considerable modification. In 1984, AABB recommended that the full cross match could be replaced by an abbreviated cross match in patients with negative antibody screen. However, before implementation of such a policy, issue regarding safety of T & S needs to be evaluated.ObjectivesThe aim of pretransfusion testing (PTT) is to ensure that enough red blood cells (RBCs) in the selected red cell components will survive when transfused.Results And ConclusionWe have, therefore in this study; evaluated safety of T & S procedure for PTT in comparison with conventional test tube cross match. The T & S procedure gave a safety of 91.6%. Also, the usefulness of the T & S was shown through the detection of unexpected antibodies in 0.75% (15 out of 2026) of cases.
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