• J A Sanchez-Izquierdo Riera, R Montoiro Allué, T Tomasa Irriguible, E Palencia Herrejón, F Cota Delgado, and C Pérez Calvo.
• Intensive Care Medicine, Hospital Universitario 12 de Octubre, Madrid, Spain. Electronic address: jasiruci@gmail.com.
• Med Intensiva. 2016 Oct 1; 40 (7): 434-47.

AbstractWe maintain a dynamic position on extracorporeal blood purification therapies (EBPT). Continuous therapies are of choice in the hemodynamically unstable patient. We recommend their early introduction in the course of the disease, and starting with a dose of 30-35mL/kg/h. Above all, however, daily re-evaluation is required of the hemodynamic and metabolic situation and water balance of our patients in order to allow dynamic dose adjustment. Some data suggest that continuous EBPT can favorably influence the clinical course of our patients, even in the absence of acute kidney injury. The potential usefulness of hemofiltration at doses higher than the conventional doses (continuous ultrafiltration >50mL/kg/h or pulses of at least 4h a day to more than 100dosesmL/kg/h) for achieving blood purification has also been commented. We review the possible indications of this technique, together with the peculiarities of implementing these therapies in children.Copyright © 2016 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

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