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Sleep medicine reviews · Dec 2010
ReviewPatent foramen ovale and obstructive sleep apnea: a new association?
- Edmund M T Lau, Brendon J Yee, Ronald R Grunstein, and David S Celermajer.
- Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital, Camperdown NSW 2050, Australia. emtlau@bigpond.com
- Sleep Med Rev. 2010 Dec 1; 14 (6): 391-5.
AbstractPatent foramen ovale (PFO) is a common congenital cardiac defect of the atrial septal wall affecting up to 25% of the population. PFO has received much clinical interest because it has been implicated in disease states such as stroke, migraine and decompression illness. More recently, there has been emerging evidence to support a clinically important relationship between PFO and obstructive sleep apnea (OSA). Furthermore, minimally invasive percutaneous techniques are now available for closure of PFO. We will review the current state of knowledge in the relationship between PFO and OSA, with emphasis on the pathophysiological interactions and clinical implications of this association.Crown Copyright © 2010. Published by Elsevier Ltd. All rights reserved.
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