• Pediatric neurology · Feb 2012

    Case Reports

    Hashimoto encephalopathy causing drug-resistant status epilepticus treated with plasmapheresis.

    • Ömer Bektas, Arzu Yılmaz, Tanıl Kendirli, Zeynep Sıklar, and Gülhis Deda.
    • Department of Pediatric Neurology, Ankara University Medical School, Ankara, Turkey. bektasomer@gmail.com
    • Pediatr. Neurol. 2012 Feb 1; 46 (2): 132-5.

    AbstractHashimoto encephalopathy is a rare, clinically heterogenous condition. Its treatment is based on corticosteroids. A previously normal 12-year-old boy was admitted to our pediatric emergency department with status epilepticus. He experienced a recurrence of status epilepticus after pentobarbital withdrawal, and required repeated resumptions of drug-induced coma. He manifested acute personality changes. His limbic encephalitis markers were normal, but his level of anti-thyroid peroxidase antibody was high. A diagnosis of Hashimoto encephalopathy was considered. Our patient responded to plasmapheresis instead of corticosteroid treatment. This case report is the first, to the best of our knowledge, of plasmapheresis because of Hashimoto encephalopathy in a child.Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

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