• J. Neurol. Sci. · Oct 2009

    Case Reports

    Reversible metronidazole-induced cerebellar toxicity in a multiple transplant recipient.

    • Tracey D Graves, Marie Condon, Marina Loucaidou, and Richard J Perry.
    • Department of Neurology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0NS, United Kingdom.
    • J. Neurol. Sci. 2009 Oct 15; 285 (1-2): 238-40.

    AbstractMetronidazole-induced central nervous system (CNS) toxicity causes a spectrum of neurological symptoms including ataxia, encephalopathy and peripheral neuropathy. It is associated with characteristic MRI changes of high signal intensity in the dentate nuclei. Given the increasing use of metronidazole, it is import to recognise this drug as a cause of ataxia, as it is entirely reversible on drug withdrawal.

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