• Jeremy J Reynolds, Roba Khundkar, Stefano Boriani, Richard Williams, Laurence D Rhines, Norio Kawahara, Jean-Paul Wolinsky, Ziya L Gokaslan, and Peter P Varga.
• Oxford Spinal Unit, Oxford University Hospitals, Oxford, UK.
• Spine. 2016 Oct 15; 41 Suppl 20: S199S204S199-S204.

Study DesignSystematic review and expert consensus.ObjectiveTo address the following two questions: (A) Is there a difference in outcomes after spino-pelvic reconstruction of total sacrectomy defects compared with no reconstruction? (B) What constitutes best surgical technique for soft tissue and bony reconstruction after total sacrectomy?Summary Of Background DataThe management of the soft tissue and bony defect after total sacrectomy for primary sacral tumors remains a challenge due to the complex anatomical relationships and biomechanical requirements. The scarcity of evidence-based literature in this specialized field makes it difficult for the treating surgeon to make an informed choice.MethodsA systematic literature review was performed (1950-2015), followed by a meeting of an international expert panel. Medline, Embase, and CINAHL databases and Cochrane Libraries were searched. Using the GRADE guidelines, the panel of experts formulated recommendations based on the available evidence.ResultsThree hundred fifty-three studies were identified. Of these, 17 studies were included and were case series. Seven were evaluated as high quality of evidence and nine were of low quality. There were a total of 116 participants. Three studies included patients (n = 24) with no spino-pelvic reconstruction. One study included patients (n = 3) with vascularized bone reconstruction. Twelve studies included patients (n = 80) with no soft tissue reconstruction, three studies described patients with a local flap (n = 20), and four studies with patients having regional flap reconstruction (n = 16). Patients with or without spino-pelvic reconstruction had similar outcomes with regards to walking; however, most patients in the nonreconstructed group had some ilio-lumbar ligamentous stability preserved. The wound dehiscence and return to theater rates were higher in patients with no soft tissue reconstruction.ConclusionWe recommend spino-pelvic reconstruction be undertaken with soft tissue reconstruction after total sacrectomy.Level Of EvidenceN/A.

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