• Susan M Tarlo, Kenneth W Altman, John Oppenheimer, Kaiser Lim, Anne Vertigan, David Prezant, Richard S Irwin, and CHEST Expert Cough Panel.
• Division of Respiratory Medicine, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada. Electronic address: susan.tarlo@utoronto.ca.
• Chest. 2016 Oct 1; 150 (4): 894907894-907.

BackgroundIn response to occupational and environmental exposures, cough can be an isolated symptom reflecting exposure to an irritant with little physiological consequence, or it can be a manifestation of more significant disease. This document reviews occupational and environmental contributions to chronic cough in adults, focusing on aspects not previously covered in the 2006 ACCP Cough Guideline or our more recent systematic review, and suggests an approach to investigation of these factors when suspected.MethodsMEDLINE and TOXLINE literature searches were supplemented by articles identified by the cough panel occupational and environmental subgroup members, to identify occupational and environmental aspects of chronic cough not previously covered in the 2006 ACCP Cough Guideline. Based on the literature reviews and the Delphi methodology, the cough panel occupational and environmental subgroup developed guideline suggestions that were approved after review and voting by the full cough panel.ResultsThe literature review identified relevant articles regarding: mechanisms; allergic environmental causes; chronic cough and the recreational and involuntary inhalation of tobacco and marijuana smoke; nonallergic environmental triggers; laryngeal syndromes; and occupational diseases and exposures. Consensus-based statements were developed for the approach to diagnosis due to a lack of strong evidence from published literature.ConclusionsDespite increased understanding of cough related to occupational and environmental triggers, there remains a gap between the recommended assessment of occupational and environmental causes of cough and the reported systematic assessment of these factors. There is a need for further documentation of occupational and environmental causes of cough in the future.Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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