• Hiren J Mehta, Tan-Lucien Mohammed, and Michael A Jantz.
• Division of Pulmonary, Critical Care, and Sleep Medicine, University of Florida, College of Medicine, Gainesville, FL. Electronic address: hiren.mehta@medicine.ufl.edu.
• Chest. 2017 Mar 1; 151 (3): 539-543.

AbstractLung cancer screening using low-dose CT scanning reduces lung-cancer-specific and overall mortality in high-risk patients. A significant limitation of lung cancer screening is the false-positive rate. The American College of Radiology Lung Imaging Reporting and Data System (Lung-RADS) was designed to standardize reporting of low-dose lung cancer screening results and to decrease the false-positive rate without significantly compromising sensitivity. Implementing Lung-RADS can also improve cost-effectiveness. However, Lung-RADS has never been studied in a prospective fashion. It also does not have a specific reporting category for patients with isolated hilar and mediastinal adenopathy or pleural effusion in the absence of lung nodules. We report four such cases from our lung cancer screening program. We believe that this is a significant limitation of Lung-RADS and should be revised in its new version.Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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