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Heart, lung & circulation · Mar 2014
Clinical TrialSurgical aortic valve replacement in very elderly patients aged 80 years and over: evaluation of early clinical outcomes.
- Edwin Ho, Manu N Mathur, Peter W Brady, David Marshman, Russell J Brereton, Donald E Ross, Ravinay Bhindi, and Peter S Hansen.
- Department of Cardiology, Royal North Shore Hospital, Sydney, Australia. Electronic address: ed.kk.ho@gmail.com.
- Heart Lung Circ. 2014 Mar 1; 23 (3): 242-8.
BackgroundAn increasing number of very elderly patients aged ≥80 years will require aortic valve replacement (AVR) for severe aortic stenosis (AS). Many are classified as high-risk surgical candidates. Transcatheter aortic valve implantation (TAVI) has been proposed as an alternative to surgical AVR (SAVR) for high-risk patients. We evaluated early clinical outcomes of very elderly patients undergoing SAVR to optimise TAVI candidate selection.MethodsWe conducted a retrospective case review of 132 consecutive patients aged ≥80 years undergoing isolated SAVR (49 patients) or combined SAVR/CABG (83 patients) during February 2002-January 2010 at a single tertiary referral hospital. Risk for cardiac surgery was calculated using the logistic EuroSCORE (ES(log)). Mortality and morbidity data were collected for the 30-day postoperative period.ResultsThirty-day mortality rate was 8.3% for patients undergoing SAVR (6.1% for isolated SAVR and 9.6% for SAVR/CABG). Permanent stroke occurred in 3.8% and renal insufficiency in 7.6% of the cohort. Thirty-five percent of patients had left ventricular ejection fraction <50%, 67% had advanced symptoms (NYHA class III or IV), and 42% of patients were stratified as high-risk (ES(log)≥20%).ConclusionsSAVR can be performed in very elderly patients with acceptable operative morbidity and mortality. The outcomes at our institution are comparable to contemporary SAVR and TAVI outcomes.Crown Copyright © 2013. Published by Elsevier B.V. All rights reserved.
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