• Jamal McClendon, Timothy R Smith, Patrick A Sugrue, Sara E Thompson, Brian A O'Shaughnessy, and Tyler R Koski.
• Division of Pediatric Neurosurgery, Phoenix Children's Hospital, Phoenix, Arizona, USA. Electronic address: jmcclendon@phoenixchildrens.com.
• World Neurosurg. 2016 Nov 1; 95: 419-424.

ObjectiveTo evaluate spinal implant density and proximal junctional kyphosis (PJK) in adult spinal deformity (ASD).MethodsConsecutive patients with ASD receiving ≥5 level fusions were retrospectively analyzed between 2007 and 2010.Inclusion CriteriaASD, elective fusions, minimum 2-year follow-up.Exclusion Criteriaage <18 years, neuromuscular or congenital scoliosis, cervical or cervicothoracic fusions, nonelective conditions (infection, tumor, trauma). Instrumented fusions were classified by the Scoliosis Research Society-Schwab ASD classification. Statistical analysis consisted of descriptives (measures of central tendency, dispersion, frequencies), independent Student t tests, χ2, analysis of variance, and logistic regression to determine association of implant density [(number of screws + number of hooks)/surgical levels of fusion] and PJK. Mean and median follow-up was 2.8 and 2.7 years, respectively.ResultsEighty-three patients (17 male, 66 female) with a mean age of 59.7 years (standard deviation, 10.3) were analyzed. Mean body mass index (BMI) was 29.5 kg/m2 (range, 18-56 kg/m2) with mean preoperative Oswestry Disability Index of 48.67 (range, 6-86) and mean preoperative sagittal vertical axis of 8.42. The mean levels fused were 9.95 where 54 surgeries had interbody fusion. PJK prevalence was 21.7%, and pseudoarthrosis was 19.3%. Mean postoperative Oswestry Disability Index was 27.4 (range, 0-74). Independent Student t tests showed that PJK was not significant for age, gender, BMI, rod type, mean postoperative sagittal vertical axis, or Scoliosis Research Society-Schwab ASD classification; but iliac fixation approached significance (P = 0.077). Implant density and postoperative lumbar lordosis (LL) were predictors for PJK (P = 0.018 and 0.045, respectively). Controlling for age, BMI, and gender, postoperative LL (not implant density) continued to show significance in multivariate logistic regression model.ConclusionsPJK, although influenced by a multitude of factors, may be statistically related to implant density and LL.Copyright © 2016. Published by Elsevier Inc.

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