• Seminars in nephrology · Jan 2015

    Review

    Entanglement of sepsis, chronic kidney disease, and other comorbidities in patients who develop acute kidney injury.

    • Michael Heung and Jay L Koyner.
    • Division of Nephrology, Department of Medicine, University of Michigan, Ann Arbor, MI. Electronic address: mheung@umich.edu.
    • Semin. Nephrol. 2015 Jan 1; 35 (1): 23-37.

    AbstractAcute kidney injury (AKI) is a common and severe complication for patients in the intensive care setting, often occurring in the setting of sepsis. Both sepsis and AKI are complex and heterogeneous syndromes with overlapping risk factors. Comorbidities - such as chronic kidney disease, diabetes mellitus, liver disease, cardiac disease and cancer - may contribute to the development of these syndromes and complicate their management. Recognition of the complex interplay between comorbid conditions, sepsis, and AKI is key to the successful management of these syndromes.Copyright © 2015 Elsevier Inc. All rights reserved.

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