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- Takeharu Koga, Tomoko Kamimura, Yuichi Oshita, Yuko Narita, Tatsuya Mukaino, Munetsugu Nishimura, Yusuke Mizoguchi, and Hisamichi Aizawa.
- First Department of Internal Medicine, Kurume University School of Medicine, Kurume, Japan. kogat@med.kurume-u.ac.jp
- J Asthma. 2006 Jan 1; 43 (1): 71-4.
AbstractShort-term bronchodilator responsiveness to an inhaled ss 2 adrenergic agonist was assessed by changes in forced expiratory volume in 1 second (FEV(1)) in nonsmoking adults with controlled asthma (mild disease, 20 patients; moderate disease, 20 patients; severe disease, 18 patients). Responsiveness correlated significantly with age and with percent of predicted FEV(1) (%FEV(1)) except in patients with severe asthma, who showed significantly less responsiveness than others. Thus, responsiveness is closely associated with degree of airflow limitation in patients with controlled asthma and is significantly influenced by severity of disease and by aging.
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