• Med Klin Intensivmed Notfmed · Apr 2014

    Review

    [Pitfalls in determining resistance].

    • A C Rodloff.
    • Institut für Medizinische Mikrobiologie und Infektionsepidemiologie, Liebigstr. 21, 04103, Leipzig, Deutschland, acr@medizin.uni-leipzig.de.
    • Med Klin Intensivmed Notfmed. 2014 Apr 1; 109 (3): 182-6.

    AbstractSelection of the optimal antimicrobial therapy is often crucial for the morbidity and mortality associated with an infection. A reliable antibiogram provides the basis for antibiotic therapy optimization. In case of life-threatening infections, minimal inhibitory concentration values should be available so that, in conjunction with knowledge of the pharmacokinetic properties of the respective antibiotics, a rational selection addressing the individual case is feasible. If only categorized results (susceptible, intermediate, resistant: S-I-R) are available, they should be established according to European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines in order to avoid therapeutic failures.

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