• Angiology · Apr 2013

    Bilirubin levels and the burden of coronary atherosclerosis in patients with STEMI.

    • Omer Sahin, Mahmut Akpek, Deniz Elcik, Serhat Karadavut, Vedat Simsek, Murat Tulmac, Ozcan Orscelik, Bekir Calapkorur, Ali Ergin, and Mehmet G Kaya.
    • Department of Cardiology, Erciyes University School of Medicine, Kayseri, Turkey.
    • Angiology. 2013 Apr 1; 64 (3): 200-4.

    AbstractWe investigated whether serum bilirubin level (a marker of heme oxygenase activity) is a predictor of high levels of SYNTAX score (SXscore) in patients with acute myocardial infarction. Patients (n = 281; male 77%; mean age 60 ± 12) who were admitted with ST-elevation myocardial infarctions (STEMIs) were enrolled. Patients were divided into 2 groups. Group 1 was defined as SXscore <22 and group 2 was defined as SXscore ≥22. Total bilirubin levels were significantly higher in the high-SXscore group than in the low-SXscore group (0.86 ± 0.42 vs 1.02 ± 0.51, P = .005). A significant correlation was detected between total bilirubin and SXscore (r = .42; P = .001). At multivariate analysis, total bilirubin (odds ratio: 1.86, 95% confidence interval 1.04-3.35; P = .038) was an independent risk factor for high SXscore in patients with STEMI. In conclusion, serum bilirubin level is independently associated with SXscore in patients with STEMI.

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