• Nishanth Sadashiva, Anil Sharma, Dhaval Shukla, Poyuran Rajalakshmi, Anita Mahadevan, and Devi Bhagavatula Indira BI Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India. Electronic address: bidevidr@gmail.com..
• Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India.
• World Neurosurg. 2016 Nov 1; 95: 618.e1-618.e6.

BackgroundIntracranial extraskeletal mesenchymal chondrosarcomas (MCSs) are rare tumors accounting for <0.16% of intracranial tumors. They are usually described as occurring in the age group of 20-30 years and are commonly found in the frontoparietal region arising from the falx and surrounding dura. We describe 3 cases at varying ages, locations, and outcomes.Case DescriptionA 42-year-old woman with anterior one third falx-based lesion; a 7-year-old boy with mid one third falcine lesion with hyperostosis of bone, presenting in comatose stage; and a 52-year-old woman with left posterior lateral frontal dural-based lesion are presented. Histopathology of all cases was confirmed with immunohistochemistry. All patients underwent complete excision but had varying outcomes.ConclusionsIntracranial MCSs are rare malignant tumors with poor prognosis. Because of their rarity, it may not be considered as a differential diagnosis and it is often misdiagnosed radiologically, but the importance lies in the need of radical excision. The potential effect of postoperative radiotherapy and chemotherapy is controversial. This article sheds some light on variable prognosis of this tumor.Copyright © 2016 Elsevier Inc. All rights reserved.

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