• Crit Care · Jan 2008

    Editorial Comment Comparative Study

    Circuit lifespan during continuous renal replacement therapy: children and adults are not equal.

    • Zaccaria Ricci, Isabella Guzzo, Stefano Picca, and Sergio Picardo.
    • Department of Pediatric Cardiology, Bambino Gesù Hospital, Piazza S. Onofrio 4 00100, Rome, Italy. zaccaria.ricci@fastwebnet.it
    • Crit Care. 2008 Jan 1; 12 (5): 178.

    AbstractIn the field of continuous renal replacement therapy (CRRT), session length, downtime and dose require detailed research, which will provide information important in relation to prescription, anticoagulation and circuit material choice (membrane type and size, vascular access site and size). In particular, it appears that many of the data currently existing in the literature and accepted regarding CRRT prescription and delivery in critically ill adult patients are not strictly applicable to the paediatric setting. Furthermore, many of the available paediatric studies are small, retrospective or underpowered. In paediatric CRRT, epidemiological investigations and prospective trials to investigate practical aspects of extracorporeal therapies are welcome and urgently needed.

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