• Journal of neurosurgery · Jul 1986

    Randomized Controlled Trial Clinical Trial

    Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia. A prospective study of 100 cases.

    • M J Arias.
    • J. Neurosurg. 1986 Jul 1; 65 (1): 32-6.

    AbstractA prospective study of percutaneous retrogasserian glycerol rhizotomy (PRGR) with and without metrizamide trigeminal cisternography is reported in the treatment of the trigeminal neuralgia. A series of 100 patients with typical trigeminal neuralgia were allocated randomly to two treatment groups: Group I patients received PRGR with trigeminal cisternography (50 cases) and Group II patients received PRGR without trigeminal cisternography (50 cases). The results indicate that PRGR without trigeminal cisternography is a valid alternative to the original technique. Factors that assured the accurate performance of the modified technique proposed in this study were: spontaneous cerebrospinal fluid drainage; radiologically confirmed placement of the thin spinal needle at the clival edge into the trigeminal impression of the petrous apex and in the center of the foramen ovale; a positive response to the glycerol test; clinical control of the final glycerol injection; and an alert and cooperating patient throughout the entire procedure.

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