-
Prescrire international · Aug 2010
Secondary leukaemia: after umbilical cord blood stem cell transplantation too.
- Prescrire Int. 2010 Aug 1; 19 (108): 166-7.
AbstractSince the late 1990s, umbilical cord blood stem cells have been used to treat some severe haematological disorders. In theory, this type of transplant carries a lower risk of immunological incompatibility. Ten cases of secondary leukaemia following cord blood stem cell transplantation have been published in detail, including 7 cases of acute myeloid leukaemia. The malignancies were diagnosed between 5 and 40 months after transplantation. The patients were severely immunodepressed, and analysis showed that the leukaemias were of donor cell origin. Patients receiving cord blood stem cell grafts, like all transplant recipients, should therefore be monitored for secondary leukaemia.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*,_underline_or**bold**. - Superscript can be denoted by
<sup>text</sup>and subscript<sub>text</sub>. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3., hyphens-or asterisks*. - Links can be included with:
[my link to pubmed](http://pubmed.com) - Images can be included with:
 - For footnotes use
[^1](This is a footnote.)inline. - Or use an inline reference
[^1]to refer to a longer footnote elseweher in the document[^1]: This is a long footnote..