• Antigona Hasani, Agreta Gecaj-Gashi, Sadik Llullaku, and Hysni Jashari.
• Department of Anesthesiology and Reanimation, University Clinical Centre of Kosova, Prishtina, Kosovo. antigona.hasani@gmail.com
• Pain Med. 2013 Mar 1;14(3):442-6.

ObjectivePostoperative analgesia remains a problem, especially in pediatric patients. We hypothesize that patients anesthetized with sevoflurane have more postoperative pain than with propofol.DesignRandomized, prospective, double-blind study.SettingUniversity teaching hospital.SubjectsThe subjects were 88 premedicated children, aged 3-6 years, and American Society of Anesthesiologists (ASA) Physical Status I or II.InterventionsSubjectsunderwent hernia repair surgery.MethodsAnesthesia was maintained with propofol (group P, N = 46) or sevoflurane (group S, N = 42) and fentanyl was administered during surgery. All children before surgical incision received 40 mg/kg paracetamol, rectally. Prior to wound closure, the margins were infiltrated with 0.5% bupivacaine.Outcome MeasuresThe primary outcome was pain score assessed by Faces Pain Scale (FPS) 2 hours postoperatively. The secondary outcomes included recovery time and adverse events within the first 2 hours.ResultsGroup S had a significantly higher proportion of patients who exhibited postoperative pain than group P (24.3% vs 4.5%, respectively; P < 0.05). FPS score in group P was 1.2 ± 0.6, compared with 3.4 ± 1.5 in group S (P < 0.001). Mean recovery time in group S was significantly shorter than the corresponding mean for group P (10.1 ± 1.3 vs 16.5 ± 5.4 minutes, respectively; P < 0.001).ConclusionIn children, anesthesia maintenance with propofol was associated with a significantly lower incidence of postoperative pain than with sevoflurane.Wiley Periodicals, Inc.

29 keywords...

hide…