• World Neurosurg · Dec 2016

    Case Reports

    Caulobacter spp: A rare pathogen responsible for paucisintomatic persisitant meningitis in a glioblastoma patient.

    • Federica Penner, Silvia Brossa, Anna Maria Barbui, Alessandro Ducati, Rossana Cavallo, and Francesco Zenga.
    • Division of Neurosurgery, Department of Neuroscience, University of Torino, Turin, Italy. Electronic address: federica.penner@gmail.com.
    • World Neurosurg. 2016 Dec 1; 96: 611.e11-611.e13.

    BackgroundCaulobacter spp. are Gram-negative bacteria that have rarely been found to be pathogenic in humans.Case DescriptionThis report describes the first case, to our knowledge, of meningitis in an adult patient caused by Caulobacter spp. A 75-year-old man was operated for a glioblastoma with no evident signs of primary infection in the wound site. Eight days after surgery, the patient developed signs and symptoms of meningitis. Caulobacter was then isolated on 3 separate occasions in the patient's cerebrospinal fluid. Thereafter, specific antibiotic therapy began. After 2 weeks of therapy, the patient was discharged with complete resolution of any related symptoms.ConclusionsCaulobacter spp. can cause adult meningitis even where there is no evidence of surgical site infection.Copyright © 2016 Elsevier Inc. All rights reserved.

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