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- Tomasz J Kuzniar, Rajesh Balagani, Kathryn A Radigan, Phillip Factor, and Gökhan M Mutlu.
- Division of Pulmonary and Critical Care Medicine, NorthShore University HealthSystem, Evanston, IL, USA.
- Am J Ther. 2010 Sep 1; 17 (5): e172-4.
AbstractZolpidem is a nonbenzodiazepine hypnotic with a favorable adverse effect profile. There are single reports of respiratory decompensation associated with zolpidem overdose. We report a case ofa young woman with depression who developed deep coma with respiratory failure and a loss of brainstem reflexes as a result of zolpidem overdose. Supportive management led to a complete recovery of neurologic function. Acute zolpidem overdose should be considered in the differential diagnosis of coma with absent brainstem reflexes.
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