• Chest · Dec 2016

    Multicenter Study

    Association between insomnia and asthma burden in the Severe Asthma Research Program (SARP) III.

    • Faith S Luyster, Patrick J Strollo, Fernando Holguin, Mario Castro, Eleanor M Dunican, John Fahy, Benjamin Gaston, Elliot Israel, Nizar N Jarjour, David T Mauger, Wendy C Moore, and Sally E Wenzel.
    • School of Nursing, University of Pittsburgh, Pittsburgh, PA. Electronic address: luysterfs@upmc.edu.
    • Chest. 2016 Dec 1; 150 (6): 1242-1250.

    BackgroundSleep difficulties are commonly reported by patients with asthma; however, the prevalence of insomnia and its association with disease burden and well-being is unknown. We aimed to determine the prevalence of insomnia, defined as combined sleep-specific complaints with associated daytime symptoms, among a large sample of adults with asthma, and to compare well-being, asthma control, and asthma-related health care utilization in individuals with asthma and insomnia and those without insomnia.MethodsBaseline data from adults with physician-confirmed asthma enrolled in the Severe Asthma Research Program III was used for analyses (N = 714). Participants completed the Insomnia Severity Index (ISI), Asthma Control Test, Asthma Quality of Life Questionnaire, and Hospital Anxiety and Depression Scale.ResultsInsomnia (ISI ≥ 10) was identified in 263 participants (37%). Presence of insomnia was associated with higher levels of depression and anxiety symptoms and poorer quality of life. Those with insomnia had a 2.4-fold increased risk for having not well-controlled asthma and a 1.5-fold increased risk for asthma-related health care utilization in the past year compared with those without insomnia.ConclusionsInsomnia is highly prevalent in asthma and is associated with adverse outcomes. Further studies are needed to gain a better understanding of the interaction between insomnia and asthma control.Copyright © 2016 American College of Chest Physicians. Published by Elsevier Inc. All rights reserved.

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