• Lancet · Oct 2016

    Comment Review

    Pathophysiology, research challenges, and clinical management of smoke inhalation injury.

    • Perenlei Enkhbaatar, Basil A Pruitt, Oscar Suman, Ronald Mlcak, Steven E Wolf, Hiroyuki Sakurai, and David N Herndon.
    • Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA. Electronic address: peenkhba@utmb.edu.
    • Lancet. 2016 Oct 1; 388 (10052): 143714461437-1446.

    AbstractSmoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. However, relatively little attention has been paid to this devastating condition, and the bulk of research is limited to preclinical basic science studies. Moreover, no worldwide consensus criteria exist for its diagnosis, severity grading, and prognosis. Therapeutic approaches are highly variable depending on the country and burn centre or hospital. In this Series paper, we discuss understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management.Copyright © 2016 Elsevier Ltd. All rights reserved.

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