• Anasthesiol Intensivmed Notfallmed Schmerzther · Oct 2016

    Review

    [Remote Ischaemic Conditioning - an overview].

    • Christian Stoppe, Patrick Meybohm, and Andreas Goetzenich.
    • Klinik für Operative Intensivmedizin, Uniklinik RWTH Aachen.
    • Anasthesiol Intensivmed Notfallmed Schmerzther. 2016 Oct 1; 51 (10): 596-603.

    AbstractThe strategy of Remote Ischaemic Conditionings (RIC) is easy to apply, cost effective, low in side effects and belongs to the most potent cardioprotective strategies evaluated within recent years. Its practical application is carried out by simple use of a blood pressure cuff, more precise by 4 repetitive cycles of inflating the cuff above 200 mmHg for 5 minutes followed by an equal long break between the cycles. First experimental and clinical data repetitively demonstrated a significant reduction in myocardial injury following ischemia/reperfusion. Nevertheless, given the neutral results of two recent clinical multicentre trials, the clinical significance and benefits of RIC in cardiac surgery patients remains uncertain. The combination of co-medication and narcotic agents is thought to be responsible for the failed transfer into the clinical practice.© Georg Thieme Verlag Stuttgart · New York.

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