• J. Cutan. Pathol. · Dec 2006

    Case Reports

    A case of argyria after colloidal silver ingestion.

    • Anne Lynn S Chang, Vista Khosravi, and Barbara Egbert.
    • Department of Dermatology, Stanford University Medical Center, Stanford, CA 94305, USA. alschang@stanford.edu
    • J. Cutan. Pathol. 2006 Dec 1; 33 (12): 809-11.

    BackgroundArgyria is often considered an entity of the past, one which has largely disappeared with the cessation of silver usage in oral medications. However, with the practice of colloidal silver ingestion in current "alternative health" treatments, argyria should be considered in the differential diagnosis of blue-gray hyperpigmentation.MethodsA single case report with clinicopathological correlation.ResultsHistological examination of skin biopsy specimen, which showed perieccrine brown-black granules, verified that colloidal silver rather than a prescribed medication was the source of the patient's dyspigmentation.

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