• Hiroshi Yokota, Yuki Ida, Daisuke Wajima, Fumihiko Nishimura, and Hiroyuki Nakase.
• Department of Neurosurgery, Nabari City Hospital, Nabari, Mie, Japan; Department of Neurosurgery, Nara Medical University, Kashihara, Nara, Japan. Electronic address: hyokota0001@gmail.com.
• World Neurosurg. 2017 Jan 1; 97: 752.e1-752.e3.

BackgroundA Rathke cleft cyst (RCC) with nonhemorrhagic rupture mimicking pituitary apoplexy has been reported rarely.Case DescriptionA 52-year-old woman, previously diagnosed with asymptomatic RCC, came to us with a severe headache, along with visual dysfunction and symptoms of pituitary insufficiency. Fluid-attenuated inversion recovery magnetic resonance imaging demonstrated diffuse hyperintensity in the cerebral cisterns, whereas watery clear cerebrospinal fluid was obtained by lumbar puncture. Surgery performed 1 month after onset revealed a nonhemorrhagic lesion, with a final diagnosis of nonhemorrhagic RCC rupture.ConclusionsWe conclude that nonhemorrhagic RCC rupture and subsequent leakage of the contents into subarachnoid space were the underlying pathogenesis in the present case of RCC resembling apoplexy.Copyright © 2016 Elsevier Inc. All rights reserved.

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