• Ann Emerg Med · Jan 2017

    Case Reports

    Intranasal Dexmedetomidine Sedation as Adjuvant Therapy in Acute Asthma Exacerbation With Marked Anxiety and Agitation.

    • Giorgio Cozzi, Sara Lega, Rita Giorgi, and Egidio Barbi.
    • Institute for Maternal and Child Health IRCCS Burlo Garofolo, Trieste, Italy.
    • Ann Emerg Med. 2017 Jan 1; 69 (1): 125-127.

    AbstractWe describe 2 patients with acute asthma exacerbation who were admitted to the emergency department (ED) with severe agitation and restlessness as a prominent finding, for which bedside asthma treatment sedation with intranasal dexmedetomidine was performed. In both cases, dexmedetomidine allowed the patients to rest and improved tolerance to treatment. Dexmedetomidine is a unique sedative with an excellent safety profile and minimal effect on respiratory function. These properties render it particularly promising for the management of severe agitation in children admitted to the ED with acute asthma exacerbation.Copyright © 2016 American College of Emergency Physicians. Published by Elsevier Inc. All rights reserved.

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