• J Neurosurg Spine · Oct 2007

    Case Reports

    Hypertrophic spinal pachymeningitis associated with heavy-chain disease. Case report.

    • Kazuki Yunokawa, Yoshitaka Hagiyama, Yu Mochizuki, Nobuhiro Tanaka, and Mitsuo Ochi.
    • Department of Orthopedic Surgery, Matsuyama City Hospital, Matsuyama City, Japan. yunoka@xk9.so-net.ne.jp
    • J Neurosurg Spine. 2007 Oct 1; 7 (4): 459-62.

    AbstractThe authors present a case of concurrent hypertrophic spinal pachymeningitis (HSP) and heavy-chain disease (HCD). The patient was a 71-year-old woman presenting with leg paralysis and fever. Laminectomy was performed for thoracic HSP, and chemotherapy was administered for HCD. Because the dura mater was not surgically opened, marked hypertrophy remained postoperatively. Once the HCD was controlled by chemotherapy, the fever subsided and the hypertrophy was resolved. No previous reports have supported a link between the two diseases. Idiopathic HSP may be secondary to rare conditions such as HCD, and systemic examinations should be performed to the fullest extent possible to investigate the possibility of some underlying disease.

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