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- Boris Bigalke, Karin Klingel, Andreas E May, Reinhard Kandolf, and Meinrad Gawaz Gawaz.
- Medizinische Klinik III, University Hospital of Tübingen, Tübingen, Germany. boris.bigalke@med.uni-tuebingen.de
- Can J Cardiol. 2007 Apr 1; 23 (5): 393-5.
AbstractA 67-year-old woman who presented with acute chest pain is reported. Three days before admission, she suffered from a flu-like infection. Coronary angiography showed no coronary stenosis. Ventriculography showed moderately reduced left ventricular function characterized by the so-called 'apical ballooning'. Endomyocardial biopsies and polymerase chain reaction analysis of the plasma revealed an acute infection with human herpesvirus 6 subtype A. Histological and immunohistochemical analyses revealed myocarditis with areas of interstitial macrophages and fibrosis. The present case report links, for the first time, myocarditis with a human herpesvirus 6 subtype A infection and the appearance of apical ballooning.
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