• World Neurosurg · Jan 2017

    Review Case Reports

    Long-term Survival Primary Intracranial Plasmablastic Lymphoma: Case Report and Review of the Literature.

    • Hui Ma, Ming-Hai Wei, Hua-Min Qin, Guan-Yu Wang, and Zeng-Chun Hu.
    • Department of Pharmacology, the Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, PR China.
    • World Neurosurg. 2017 Jan 1; 97: 750.e5-750.e10.

    BackgroundPrimary intracranial plasmablastic lymphoma (PIPBL) is a rare malignant tumor.Case DescriptionWe present a case of PIPBL in a 32-year-old man who complained of a progressive growing, painful mass on the right parieto-occipital part of head. Computed tomography and magnetic resonance imaging revealed a homogeneously enhanced mass with partial bone destruction. The patient underwent total resection and cranioplasty in one stage. Histopathologic examination showed large tumor cells with immunoblast-like nuclei. Immunohistochemical staining displayed CD38(+), CD138(+), Mum-1(+), CD20(-), and PAX-5(-). The patient received chemotherapy. The patient has survived more than 3.5 years after operation, with follow-up. We also review the clinical data, molecular pathologic traits, treatment, and prognosis of additional 6 cases with PIPBL in the literature.ConclusionsThis study provides important clinical information for the diagnosis and treatment of PIPBL.Copyright © 2016 Elsevier Inc. All rights reserved.

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