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- Fiona McCarthy, Rozita Roshani, Jeremy Steele, and Thorsten Hagemann.
- 1.Barts Cancer Institute, Queen Mary, University of London, Charterhouse Square, London, EC1M 6BQ, UK. t.hagemann@qmul.ac.uk.
- J. Leukoc. Biol. 2013 Dec 1; 94 (6): 1201-6.
AbstractNSCLC remains one of the most challenging malignancies to treat. Despite the introduction of innovative therapies over the last decade, the 5-year survival of NSCLC is still <20%. Clearly, novel, therapeutic approaches are required. Targeting the immune system to derive meaningful clinical benefit has proved successful in various malignancies in recent years. As a result, there is renewed focus on the use of immunotherapy in lung cancer. In this review, we provide an overview of current immune-modulatory approaches in the treatment of NSCLC.
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