• Francisco Javier Martín-Sánchez, Esther Rodríguez-Adrada, Christian Mueller, María Teresa Vidán, Michael Christ, Frank Peacock W W Department of Emergency Medicine, Baylor College of Medicine, Houston, TX., Miguel Alberto Rizzi, Aitor Alquezar, Pascual Piñera, Aragues Paula Lázaro PL Emergency Department, Hospital Reina Sofia, Murcia, Spain., Pere Llorens, Pablo Herrero, Javier Jacob, Cristina Fernández, and Òscar Miró.
• Emergency Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdISSC), Madrid, Spain.
• Acad Emerg Med. 2017 Mar 1; 24 (3): 298-307.

ObjectiveThe objective was to determine the effect of frailty on risk of 30-day mortality in nonseverely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs).MethodologyThe Frailty-AHF Study is a retrospective analysis of a multicenter, observational, prospective, cohort study (Older-AHF Register). This study included consecutive patients ≥ 65 years of age without severe functional dependence or dementia attended for AHF in three Spanish EDs for 4 months. Frailty was defined by frailty phenotype as the presence of three or more domains. Baseline and episode characteristics and 30-day mortality were collected in all the patients.ResultsA total of 465 patients with a mean (±SD) age of 82 (±7) years were included, 283 (61.0%) being female and 225 (51.3%) with severe comorbidity (Charlson index ≥ 3). Frailty was present in 169 (36.3%). The rate of 30-day mortality was 7.3%. Frailty adjusted for potential confounding factors was an independent factor associated with 30-day mortality (adjusted hazard ratio = 2.5; 95% confidence interval = 1.0 to 6.0; p = 0.047).ConclusionThe presence of frailty is an independent risk factor of 30-day mortality in nonsevere dependent older patients attended with AHF in EDs.© 2016 by the Society for Academic Emergency Medicine.

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